App Framework is not a new HTML5 mobile framework. Now owned by Inter its used to be called jqMoby. Like Sencha Touch it was used to make more native like hybrid mobile applications and at the same time this is a biggest difference between it and jQuery Mobile. jQuery Mobile was never intended to be used only as a HTML5/CSS3 hybrid mobile app framework. On a similar track like its older brothers jQuery and jQuery UI it was intended to be used as a robust responsive solution in ever growing mobile web application market. What it took from its older brother was a all around browser support. It can be executed in every possible and available HTML5 browser and it will work just the same.